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KMID : 0369819810110020216
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Jorunal of Korean Pharmaceutical Sciences
1981 Volume.11 No. 2 p.216 ~ p.219
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Some Factors Influencing the Dissolution Rate of Lorazepam Formulations
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이창기/Lee CK
송인정/최정용/서성원/Song IJ/Choi JY/Suh SW
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Abstract
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The effect of diluents and lubricants on the dissolution rate of lorazepam was studied. The results were as following. 1. An average order of dissolution rate can be stated as; lactose> avicel> starch> kaolin. 2. The effects of lubicants is not significant generally but in the case of starch the dissolution rate is greatly effected by magnesium stearate.
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